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KMID : 1144320150470040256
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감염과 화학요법
2015 Volume.47 No. 4 p.256 ~ p.260
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Infected Aortic Aneurysm caused by Mycobacterium bovis after Intravesical Bacillus Calmette-Guerin Treatment for Bladder Cancer
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Nam Eun-Young
Na Sun-Hee
Kim Se-Yong
Yoon Do-Ran
Kim Chung-Jong
Park Kyoung-Un
Min Seung-Kee
Lee Sang-Eun
Choe Pyoeng-Gyun
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Abstract
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A 70-year-old man presented with lower back pain and cyanotic changes in his left lower extremity. He was diagnosed with infected aortic aneurysm and infectious spondylitis. He had received intravesical Bacillus Calmette-Guerin (BCG) therapy up to 1 month before the onset of symptoms. The aneurysm was excised and an aorto-biiliac interposition graft was performed. Mycobacterium tuberculosis complex was cultured in the surgical specimens. Real-time polymerase chain reaction (PCR) targeting the senX3-regX3 region, and multiplex PCR using dual-priming oligonucleotide primers targeting the RD1 gene, revealed that the organism isolated was Mycobacterium bovis BCG. The patient took anti-tuberculosis medication for 1 year, and there was no evidence of recurrence at 18 months follow-up.
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KEYWORD
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Mycobacterium bovis, Aneurysm, Infected, Spondylitis, Administration, intravesical
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